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Other Development Activities

Compound Development Phase Method of action Indication(s)
S-2367 Phase IIb NPY Y5 receptor antagonist Obesity  
S-777469 Phase I Cannabinoid 2 receptor agonist Atopic Dermatitis
S-555739 Phase I Prostoglandin D2 receptor antagonist Allergic Rhinitis
S-888711 Phase I Thrombopoietin receptor agonist Thromboeytopenia

Spotlight on S-2367

S-2367 is an oral, centrally acting anti-obesity drug which reduces appetite and enhances energy expenditure. Findings from a Phase I single-dose study indicate that S-2367 is very well tolerated with a low incidence of adverse events. S-2367 is currently in Phase II clinical testing for the treatment of obesity.

Shionogi USA is currently evaluating several other innovative compounds from Shionogi Research Laboratories in Japan to identify additional candidates for clinical development in the US. To see the Shionogi Research Laboratory development pipeline please click here.