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Development Activities at Shionogi USA

Shionogi USA currently supports the clinical development of several compounds for the treatment of HIV/AIDS, neurological conditions, and asthma.

Compound Development Phase Method of action Indication(s)
S-2367 Phase IIb NPY Y5 receptor antagonist Obesity
S-777469 Phase II Cannabinoid 2 receptor agonist Atopic Dermatitis
S-349572* Phase I Integrase Inhibitor HIV
S-265744/S-247303* Phase I (in preparation) Integrase inhibitor HIV
S-555739 Phase I Prostoglandin D2 receptor antagonist
Allergic Rhinitis
S-888711 Phase I Thrombopoietin receptor agonist Thrombocytopenia
S-0139 Phase II Endothelin a receptor antagonist Stroke
S-0373 Pre-clinical Thyrotropin releasing hormone analogue Spino-cerebellar ataxia

Compounds marked by * are being developed through Shionogi-GlaxoSmithKline Pharmaceuticals, LLC, a joint venture that Shionogi USA supports.

In addition, Shionogi USA expects to further expand it’s portfolio to include additional compounds originated by Shionogi Research Laboratories in Japan.

To learn more about our R&D activities, click on the following headings:

HIV
Neurology
Other areas